SPZ1

Spermatogenic leucine zipper protein 1 is a protein that in humans is encoded by the SPZ1 gene.[5][6][7][8][9][10]

SPZ1
Identifiers
AliasesSPZ1, NYD-TSP1, PPP1R148, spermatogenic leucine zipper 1, CILD38
External IDsOMIM: 618068 MGI: 1930801 HomoloGene: 49934 GeneCards: SPZ1
Gene location (Human)
Chr.Chromosome 5 (human)[1]
Band5q14.1Start80,319,625 bp[1]
End80,321,842 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

84654

79401

Ensembl

ENSG00000164299

ENSMUSG00000046957

UniProt

Q9BXG8

Q99MY0

RefSeq (mRNA)

NM_032567

NM_030237

RefSeq (protein)

NP_115956

NP_084513

Location (UCSC)Chr 5: 80.32 – 80.32 MbChr 13: 92.57 – 92.58 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References

  1. GRCh38: Ensembl release 89: ENSG00000164299 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000046957 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hsu SH, Shyu HW, Hsieh-Li HM, Li H (Feb 2001). "Spz1, a novel bHLH-Zip protein, is specifically expressed in testis". Mech Dev. 100 (2): 177–87. doi:10.1016/S0925-4773(00)00513-X. PMID 11165476. S2CID 17206805.
  6. Sha JH, Zhou ZM, Li JM, Lin M, Zhu H, Zhu H, Zhou YD, Wang LL, Wang YQ, Zhou KY (Jun 2003). "Expression of a novel bHLH-Zip gene in human testis". Asian J Androl. 5 (2): 83–8. PMID 12778315.
  7. Hrabchak C, Varmuza S (Aug 2004). "Identification of the spermatogenic zip protein Spz1 as a putative protein phosphatase-1 (PP1) regulatory protein that specifically binds the PP1cgamma2 splice variant in mouse testis". J Biol Chem. 279 (35): 37079–86. doi:10.1074/jbc.M403710200. PMID 15226296.
  8. Horowitz E, Zhang Z, Jones BH, Moss SB, Ho C, Wood JR, Wang X, Sammel MD, Strauss JF 3rd (Apr 2005). "Patterns of expression of sperm flagellar genes: early expression of genes encoding axonemal proteins during the spermatogenic cycle and shared features of promoters of genes encoding central apparatus proteins". Mol Hum Reprod. 11 (4): 307–17. doi:10.1093/molehr/gah163. PMID 15829580.
  9. Hsu SH, Hsieh-Li HM, Huang HY, Huang PH, Li H (May 2005). "bHLH-zip transcription factor Spz1 mediates mitogen-activated protein kinase cell proliferation, transformation, and tumorigenesis". Cancer Res. 65 (10): 4041–50. doi:10.1158/0008-5472.CAN-04-3658. PMID 15899793.
  10. "Entrez Gene: SPZ1 spermatogenic leucine zipper 1".

Further reading


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