Thymosin beta-4, Y-chromosomal

Thymosin beta-4, Y-chromosomal is a protein that in humans is encoded by the TMSB4Y gene.[3][4]

TMSB4Y
Identifiers
AliasesTMSB4Y, TB4Y, thymosin beta 4, Y-linked, thymosin beta 4 Y-linked
External IDsOMIM: 400017 GeneCards: TMSB4Y
Gene location (Human)
Chr.Y chromosome (human)[1]
BandYq11.221Start13,703,899 bp[1]
End13,706,024 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9087

n/a

Ensembl

ENSG00000154620

n/a

UniProt

O14604

n/a

RefSeq (mRNA)

NM_004202

n/a

RefSeq (protein)

NP_004193

n/a

Location (UCSC)Chr Y: 13.7 – 13.71 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

The protein consists (in humans) of 44 amino acids (msdkpgmaei ekfdksklkk tetqeknpls sketieqerq ages) MolWt 4881.[5]

Function

This gene lies within the male specific region of chromosome Y. Its homolog on chromosome X (thymosin beta-4) escapes X inactivation and encodes an actin sequestering protein.[4]

References

  1. GRCh38: Ensembl release 89: ENSG00000154620 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Lahn BT, Page DC (October 1997). "Functional coherence of the human Y chromosome". Science. 278 (5338): 675–80. Bibcode:1997Sci...278..675L. doi:10.1126/science.278.5338.675. PMID 9381176.
  4. "Entrez Gene: TMSB4Y thymosin, beta 4, Y-linked".
  5. https://www.ncbi.nlm.nih.gov/protein/NP_004193

Further reading

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